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Translations for „nucleosome“ in the English » Polish Dictionary (Go to Polish » English)

nucleosome BIOL

Monolingual examples (not verified by PONS Editors)

English
Alternatively, the nucleosome can be partially unwrapped by thermal fluctuations allowing temporary access to the transcription factor binding site.
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Also, multiple modifications may occur at the same time, and these modifications may work together to change the behavior of the nucleosome.
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The structures of over 20 different nucleosome core particles have been solved to date, including those containing histone variants and histones from different species.
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So they make a strong ionic bond in between them to form nucleosome.
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Technically, a nucleosome is defined as the core particle plus one of these linker regions; however the word is often synonymous with the core particle.
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Both the protocols for determining open chromatin region have their own bias depending on underlying nucleosome structure.
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When a gene is undergoing transcription, its transcription start site is almost always nucleosome-free.
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In appropriate conditions, this reconstitution process allows for the nucleosome positioning affinity of a given sequence to be mapped experimentally.
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For most of other transcription factors, the nucleosome should be actively removed by molecular motors such as chromatin remodelers.
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See nucleosome, histone and chromatin.
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