Import von Proteinen in den Apicoplast von Plasmodium falciparum
In einem zweiten Projekt untersuchen wir, wie Proteine in den Apicoplast importiert werden.Dabei handelt es sich um eine Plastid-ähnliche Organelle in einzelligen Parasiten wie dem Malariaerreger Plasmodium falciparum.
Im Apicolast laufen eine Reihe essenzieller Stoffwechselreaktionen ab, zum Beispiel die Synthese von Lipiden, Häm oder Eisen-Schwefel-Clustern.
www.mpibpc.mpg.deProtein import into the apicoplast of Plasmodium falciparum
In a second project, we investigate an ERAD-like process that moves proteins into the apicoplast, a plastid-like organell in unicellular parasites, like the malaria parasite Plasmodium falciparum.
The apicoplast performs metabolic reactions essential for the parasite's survival, which include the synthesis of lipid precursors, heme and iron-sulfur clusters.
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