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Translations for „thrombin“ in the English » Arabic Dictionary (Go to Arabic » English)

thrombin N

Monolingual examples (not verified by PONS Editors)

English
It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation.
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The platelet rich plasma can be mixed with calcium and thrombin to create a product known as autologous platelet gel.
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Thrombin and fibrin glue are used surgically to treat bleeding and to thrombose aneurysms.
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Thrombin also promotes further thrombin generation, and activates platelets, stimulating aggregation and granule release.
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The latent state has the same form as the activated state - that is, when it is inhibiting thrombin.
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A newer class of drugs, the direct thrombin inhibitors, is under development; some members are already in clinical use (such as lepirudin).
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In fact thrombin is present from the very beginning, already when platelets are making the plug.
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This allows substrates to substartes to compete with cleaved bivalirudin for access to exosite 1 on thrombin.
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The protein increases the lag phase as well as the height of the peak of thrombin generation when in plasma, leading to prolonged bleeding.
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This can be contrasted with lupus anticoagulant which inhibits agglutination in the presence of thrombin.
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