Mot1 reguliert die Transkription, indem es TBP unter Energieverbrauch von der DNA ablöst.
„Wie der Komplex aus TBP und DNA von Mot1 auseinandergepflückt wird, war bisher aber noch völlig unklar“, sagt Hopfner.
www.cup.uni-muenchen.deMot1 regulates transcription by actively removing TBP from the DNA, using ATP as a source of energy.
“How Mot1 dissociates the TBP-DNA complex was completely unclear up to now,” says Hopfner.
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