heptamere Pore alpha7
Erst die Pore alpha7 ist fest in der Membran verankert und wirkt lytisch auf die Blutzelle.
Für diese Wirkung ist bei menschlichen Erythrozyten eine Konzentration von 1 µM im Blut nötig, bei Kaninchen-Erythrozyten nur 1 nM.
www.biologie.uni-hamburg.deheptameric pore alpha7
Only the pore alpha7 is steadily fastened to the membrane and able to lyse the blood cell.
To accomplish lysis of human erythrocytes a blood concentration of 1 µM is neccessary, to lyse rabbit erythrocytes 1 nM is sufficient.
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