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Translations for „sphingosine“ in the English » German Dictionary (Go to German » English)

sphingosine [ˌsfɪŋeʊsaɪn] N (amino alcohol with an unsaturated hydrocarbon chain)

Monolingual examples (not verified by PONS Editors)

English
This leads to the formation of sphingosine-1-phosphate, a potent signaling lipid.
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They were normally observed by an elevation of the sphinganine/sphingosine ratio.
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Finally, ceramide may be broken down by a ceramidase to form sphingosine.
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There is no direct route of synthesis from sphinganine to sphingosine; it has to be acylated first to dihydroceramide, which is then dehydrogenated to ceramide.
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Also, the rate of removal of the accumulated sphinganine and sphingosine will affect the detoxification.
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Sphingosine may be phosphorylated to form sphingosine-1-phosphate.
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The long-chain sphingoid bases released from the lysosome may then re-enter pathways for synthesis of ceramide and/or sphingosine-1-phosphate.
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Several variations on this basic structure exist, including alternate backbones such as sphingosine in the sphingolipids, and hydrophilic groups such as phosphate as in phospholipids.
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This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate.
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The major sphingoid base of mammals is commonly referred to as sphingosine.
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